Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Cullin 5 (Ubiquitin proteasome system protein)

Seq-ID:

Q93034 [Homo sapiens]

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Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

MINT Interaction(s):

[show]

MINT-61623 SMAD2_HUMAN
MINT-7277713 ELOA1_HUMAN

GO-Terms:

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Molecular Function	Cellular Component	Biological Process
receptor activity, calcium channel activity, ubiquitin protein ligase binding	cytosol, cullin-RING ubiquitin ligase complex	negative regulation of cell proliferation, cell cycle arrest, G1/S transition of mitotic cell cycle, induction of apoptosis by intracellular signals, interspecies interaction between organisms, ubiquitin-dependent protein catabolic process, cell proliferation

Conservation:

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Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	210	DNFEKAYLDSTERFYRTQAPS	-	18669648	HTP	1.00		-	Cullin	0.27	-	-
Y	373	PRFLTARDKAYKAVVNDATIF	-	16497976	HTP	0.14		-	Cullin	0.14	-	-
S	730	IQIMKMRKKISNAQLQTELVE	PKA_group	10898738	LTP	0.31	MOD_PKA_1	-	Cullin_Nedd8	0.16	3DPL	31.97%